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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC1
All Species:
29.39
Human Site:
S370
Identified Species:
49.74
UniProt:
Q9NV70
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV70
NP_001020095.1
894
101982
S370
S
S
T
L
A
Q
H
S
V
E
L
T
L
P
N
Chimpanzee
Pan troglodytes
XP_001142521
886
101061
F362
A
S
H
L
N
N
V
F
V
Q
Q
G
H
D
Q
Rhesus Macaque
Macaca mulatta
XP_001087347
894
101935
S370
S
S
T
L
A
Q
H
S
V
E
L
T
L
P
N
Dog
Lupus familis
XP_532380
894
102004
S370
S
S
T
L
A
Q
H
S
V
E
L
A
L
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3S6
894
101859
S370
S
S
T
L
A
Q
H
S
V
E
L
T
L
P
N
Rat
Rattus norvegicus
NP_001019941
681
76652
I204
Q
V
L
D
G
A
N
I
Q
S
I
M
A
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506171
894
101975
S370
S
S
T
L
A
Q
H
S
I
D
L
T
L
P
N
Chicken
Gallus gallus
XP_001232097
895
102211
S370
S
S
T
L
A
Q
H
S
V
E
L
T
L
P
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955891
892
101963
T370
S
S
T
L
A
Q
H
T
A
E
L
T
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVG4
889
102677
S386
I
G
D
M
Q
V
T
S
T
E
L
T
L
P
N
Honey Bee
Apis mellifera
XP_396967
859
98113
V345
R
I
K
F
S
V
I
V
A
R
H
L
N
N
L
Nematode Worm
Caenorhab. elegans
Q20678
848
97279
N336
M
K
A
Y
Q
D
R
N
D
E
L
T
A
V
D
Sea Urchin
Strong. purpuratus
XP_787291
869
100242
A345
T
N
L
Q
E
K
F
A
Q
R
L
A
I
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX85
887
100046
T384
E
L
E
K
L
K
A
T
F
V
R
R
A
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
99.5
98.5
N.A.
97.1
70.9
N.A.
95
94
N.A.
84.6
N.A.
40.1
42
34.3
49.1
Protein Similarity:
100
98.2
100
98.8
N.A.
98.6
73.8
N.A.
97.1
96.6
N.A.
91.6
N.A.
62.4
62.5
54.5
68.7
P-Site Identity:
100
20
100
93.3
N.A.
100
0
N.A.
86.6
100
N.A.
80
N.A.
46.6
0
20
6.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
13.3
N.A.
100
100
N.A.
86.6
N.A.
53.3
6.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
50
8
8
8
15
0
0
15
22
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
0
0
8
8
0
0
0
8
8
% D
% Glu:
8
0
8
0
8
0
0
0
0
58
0
0
0
0
15
% E
% Phe:
0
0
0
8
0
0
8
8
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
50
0
0
0
8
0
8
8
0
% H
% Ile:
8
8
0
0
0
0
8
8
8
0
8
0
8
0
0
% I
% Lys:
0
8
8
8
0
15
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
15
58
8
0
0
0
0
0
72
8
58
0
15
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
8
8
8
8
0
0
0
0
8
8
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% P
% Gln:
8
0
0
8
15
50
0
0
15
8
8
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
8
0
0
15
8
8
0
0
0
% R
% Ser:
50
58
0
0
8
0
0
50
0
8
0
0
0
15
0
% S
% Thr:
8
0
50
0
0
0
8
15
8
0
0
58
0
0
0
% T
% Val:
0
8
0
0
0
15
8
8
43
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _